LK26 antibody reduces growth of SKOV-3 cell xenografts in nude mice. SKOV-3 tumor cells (5 x 10⁶) were injected subcutaneously into nude mice (10 animals per group). Mice were treated with vehicle, 0.1 mg/dose of isotype-matched normal murine IgG, or 0.1 mg/dose of LK26 (precursor of MORAb-003). On day 64, tumor measurements were converted to tumor volume (in mm³) using the formula (W² x L)/2 . The P value was calculated using a double-tailed t-test.