Listeria-based anti-E7 vaccines induce regression of solid tumors in the E6/E7 transgenic mice, albeit at a lower frequency than in the WT C57BL/6 mice. 1 x 10⁵ TC-1 tumor cells were implanted s.c. at day 0 in six to eight week old mice. When palpable tumors formed seven days later, mice were i.p. immunized with 1 x 10⁸ LM-LLO-E7, 2.5 x 10⁸ LM-ActA-E7, left naive, or treated with LM-NP as a control. Mice were boosted with the same vaccine on day 14. Every seven days, tumors were measured using a caliper in two dimensions, and the average of those values was plotted against days post tumor implantations for each mouse. Values shown are only for surviving mice. Depicted is one of 3 experiments.