ADCC and/or NK cell (LAK) activity of PBMCs isolated from patients 1 and 3. Week 1 (filled circles), week 3 (open circles) and week 7 (filled triangles). (A) LAK activity of patient 1, showing increasing LAK activity during the study. (B) ADCC activity of patient 3 (cycle 2 data). An increase in ADCC activity (E:T ratio 25:1) at week 3 was observed, which decreased to baseline level by week 7.