Neo-adjuvant TIM-ILP for soft tissue sarcoma (III). The woman, 62 years old, had a gigantic, stage IV malignant fibrohistiocytoma of the left thigh that had progressed on 4 courses of systemic ifosfamide/doxorubicine. The patient had been offered hindquarter exarticulation in another town. Left: clinical aspect before TIM-ILP. The scar of the open biopsy is visible. Right: clinical aspect on day 30 after perfusion. The tumour has shrunk and there is necrosis of the biopsy scar (refer to the text).