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|
|
|
 |
|
Table 3
|
| KM871
trough serum levels determined by ELISA.
| Dose
Level
(mg/m2) |
Mean
Trough Serum KM871 Concentration ± SD (µg/mL) |
| Infusion
1 |
Infusion
2 |
Infusion
3 |
| 1 |
0 |
0.05
± 0.04 |
0.05
± 0.04 |
| 5 |
0.66
± 0.35 |
0.89
± 0.60 |
0.69
± 0.56 |
| 10 |
1.68
± 0.54 |
2.10
± 0.62 |
2.31
± 0.50 |
| 20 |
0.95
± 0.24 |
0.98
± 0.43 |
1.55
± 0.75 |
| 40 |
4.25
± 2.08 |
5.05
± 2.56 |
5.62
± 3.80 |
|
|
|
|
|
|
Copyright
© 2005 by Andrew M. Scott