|
MHC
class I and HLA-A2 expression in tumor cell lines.
|
Cell line
|
HLA-A2 typing
|
MHC
class I expression a
|
HLA-A2 expression b
|
|
Isotype control
|
- IFN-gamma
|
+ IFN-gamma
|
Isotype control
|
- IFN-gamma
|
+ IFN-gamma
|
|
SK-ES-1
|
+
|
5
|
20
|
325
|
2
|
6
|
134
|
|
SK-LMS-1
|
+
|
7
|
184
|
543
|
6
|
107
|
551
|
|
SK-UT-1
|
+
|
6
|
263
|
412
|
4
|
5
|
8
|
|
SW 872
|
+
|
6
|
84
|
121
|
5
|
187
|
630
|
|
Saos-2
|
+
|
6
|
118
|
150
|
4
|
84
|
150
|
|
HOS
|
+
|
11
|
183
|
230
|
7
|
244
|
558
|
|
MES-SA
|
-
|
6
|
28
|
245
|
3
|
5
|
6
|
|
HT-1080
|
-
|
5
|
36
|
330
|
4
|
8
|
8
|
|
SK-MEL-37
|
+
|
4
|
78
|
158
|
4
|
38
|
63
|
|
Mel 275
|
+
|
5
|
76
|
* c
|
4
|
75
|
* c
|
aMHC-class-I
expression was assessed by staining with mAb W6/32. The mean fluorescence
intensity is reported.
bHLA-A2 expression was assessed by staining with mAb BB7.2. The
mean fluorescence intensity is reported.
cCells died upon treatment with IFN-gamma.
|