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Table 1

HNSCC clones corresponding to known genes.

Functional Group

Clone ID

No. of
Times
Isolated

Identity

Unigene Cluster

Previously
Identified
by SEREX

DNA binding/
Transcription

AU-HN-2

1

TREX1, 3' repair exonuclease

Hs.278408

no

AU-HN-4

2

BRAP (BRCA1 associated): Nuclear localization protein

Hs.122764

yes

AU-HN-5

1

Trim 26 zinc finger domains

Hs.1287

no

AU-HN-10

1

GTF21 transcription factor. Murine homolog TF11-1

Hs.278589

no

AU-HN-11

6

NSEP1 (YB-1) transcription factor

Hs.74497

yes

AU-HN-16

1

MAZ transcription factor associated with c-myc

Hs.7647

yes

AU-HN-17

1

SON (DBP-5; KIAA1019; NREBP DNA binding protein)

Hs.92909

yes

AU-HN-27

1

NACA nascent polypeptide-associated complex

Hs.32916

yes

AU-HN-37

1

NUBP2 nucleotide binding protein

Hs.256549

no

RNA processing/
Translation

AU-HN-3

1

EEF2 Translation elongation factor 2

Hs.75309

no

AU-HN-13

2

GU2 Putative RNA helicase

Hs.7392

no

AU-HN-30

1

RPLI3A ribosomal protein

Hs.119122

no

AU-HN-31

1

SFRS21P (CASP11; SIP1; SRRP1290 splicing factor)

Hs.51957

no

AU-HN-33

1

RPS12 ribosomal protein

Hs.339696

no

AU-HN-34

1

MGC2835 RNA helicase

Hs.70582

no

Regulatory

AU-HN-18

1

TMF1, TATA modulatory factor

Hs.267632

yes

AU-HN-23

1

PRC1 regulator of cytokinesis

Hs.344037

no

Structural

AU-HN-22

2

KRT14 keratin 14

Hs.355214

no

AU-HN-28

1

Viniculin

Hs.75350

yes

AU-HN-32

1

H2AFY histone family member

Hs.75258

no

Apoptosis repressor

AU-HN-14

2

SLK (KIAA02304) Ste related kinase

Hs.105751

no

AU-HN-20

2

NOL3 (ARC) nuclear protein 3, apoptosis repressor

Hs.278439

no

Molecular chaperone

AU-HN-24

1

DNAJA2 member of Hsp40 family

Hs.21189

yes

AU-HN-35

1

DNAJA1 member of HSP40 family

Hs.94

yes

Other

AU-HN-1

1

LINE-1 retrotransposon

No

yes

AU-HN-6

1

MOG (HSPC 165) Homolog of yeast protein

Hs.13605

no

AU-HN-12

4

LIMS1 (PINCH): LIM and senescent antigen-like domain

Hs.112378, Hs.193700

yes

AU-HN-21

2

COPB2 coatomer protein complex subunit protein

Hs.75724

no

AU-HN-25

1

FLJ22548 hypothetical protein

Hs.103267

no

AU-HN-26

2

C21orf97; FLJ21324; MGC15873

Hs.4746

yes

AU-HN-29

3

SSNA1 Sjogrens syndrome nuclear autoantigen 1

Hs.18528

no

 

Copyright © 2004 by Jonathan Cebon