Immune response to four cancer vaccine targets.
Antigen
Tumor Expression (% of tumors)
No. of Defined T Cell Epitopes
Spontaneous Immunity (% of patients)
CD8+
CD4+
T Cell
Ab
MELAN-A / MART-1
>90
3
1
frequent
-
GP100
17
MAGE-3
30-60
11
6
rare
NY-ESO-1
25-35
4
10-20
Copyright © 2003 by Lloyd J. Old
