|
Cytotoxic
lymphocyte response to Melan-A peptide.
|
Patient
|
Day
|
Response
|
|
Pre
|
8
|
15
|
22
|
57
|
85
|
|
1
|
0
|
-
|
3
|
1
|
1
|
0
|
Na
|
|
2
|
0
|
-
|
0
|
0
|
0
|
0
|
N
|
|
3
|
0
|
-
|
0
|
0
|
-
|
-
|
N
|
|
4
|
NE
|
NE
|
-
|
-
|
-
|
-
|
NE
|
|
5
|
0
|
0
|
0
|
0
|
0
|
0
|
N
|
|
6
|
0
|
0
|
0
|
0
|
0
|
0
|
N
|
|
7
|
4
|
3
|
1
|
1
|
0
|
1
|
N
|
|
8
|
5
|
-
|
-
|
9
|
-
|
-
|
NE
|
|
9
|
0
|
-
|
-
|
3
|
-
|
-
|
NE
|
|
10
|
1
|
-
|
3
|
5
|
-
|
-
|
Y
|
|
11
|
NE
|
NE
|
-
|
-
|
-
|
-
|
NE
|
|
12
|
NE
|
NE
|
-
|
-
|
-
|
-
|
NE
|
|
13
|
1
|
0
|
1
|
0
|
1
|
1
|
N
|
|
14
|
1
|
0
|
0
|
0
|
0
|
1
|
N
|
|
15
|
0
|
0
|
0
|
0
|
0
|
0
|
N
|
|
16
|
3
|
1
|
0
|
2
|
1
|
0
|
N
|
|
17
|
0
|
-
|
1
|
0
|
0
|
0
|
N
|
|
18
|
1
|
-
|
2
|
24
|
24
|
19
|
Y
|
|
19
|
2
|
-
|
0
|
1
|
0
|
1
|
N
|
|
20
|
0
|
0
|
0
|
0
|
0
|
0
|
N
|
|
21
|
0
|
0
|
0
|
0
|
0
|
0
|
N
|
|
22
|
4
|
3
|
1
|
1
|
0
|
1
|
N
|
|
23
|
0
|
-
|
0
|
0
|
0
|
0
|
N
|
|
24
|
0
|
-
|
0
|
5
|
0
|
NE
|
Y
|
|
25
|
5
|
5
|
3
|
NE
|
NE
|
-
|
N
|
|
26
|
0
|
0
|
0
|
0
|
1
|
NE
|
N
|
|
27
|
1
|
1
|
0
|
0
|
0
|
NE
|
N
|
|
28
|
0
|
0
|
0
|
0
|
-
|
-
|
N
|
aCytotoxicity
assay was negative; however the blood was positive for Melan-A-responsive
CD8+ cells by ELIspot assay (15 spots/105 cells pre-study
increasing to 100 spots/105 cells on day 85).
|
