|
Treatment-related
adverse events for 21 non-placebo subjects evaluable for toxicity.
|
Event
|
Subjects
with Any Toxicity
|
Subjects
with Grade 3 Toxicity
|
|
No.
|
%
|
No.
|
%
|
|
Fever
|
8
|
38
|
-
|
-
|
|
Lethargy
|
8
|
38
|
-
|
-
|
|
Nausea or vomiting
|
8
|
38
|
1
|
5
|
|
Pain, including tumor pain
|
8
|
33
|
1
|
5
|
|
Headache
|
5
|
24
|
-
|
-
|
|
Arthralgia/myalgia
|
4
|
19
|
1
|
5
|
|
Subcutaneous rhIL-12 injection site reactiona
|
4
|
33
|
-
|
-
|
|
Anemia
|
3
|
14
|
-
|
-
|
|
Rigors
|
2
|
10
|
-
|
-
|
|
Gout/hyperuricemia
|
2
|
10
|
1
|
5
|
|
Lymphopenia
|
1
|
5
|
-
|
-
|
|
Sweats
|
1
|
5
|
-
|
-
|
aSubcutaneous
injection subjects only (n=12).
|
