Coordinated expression of HLA and PML in prostate cancer case 31. (a) Hematoxylin and eosin (H&E) stained section (100x). Note the existence of PIN and malignant cancer cells in the same section. (b) Expression of HLA in PIN and vascular endothelial cells but not in malignant cancer cells. (c) Similar distribution of PML expression as that of HLA shown in b. (d) Micrograph from the same section depicting the nuclear localization of PML expression in vascular endothelial cells (400x).