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Studies on the hTERT peptide540-548a.
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T cells analyzed
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hTERT transfection
of target cells
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HLA transfection
of tumor cells
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T cell recognition
correlates with antigen / HLA expression
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Reference
|
|
bulk
|
+
|
-
|
yes
|
1
|
|
bulk
|
-
|
-
|
yes
|
2
|
|
line and clones
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+
|
-
|
no
|
3
|
aAbbreviations:
"bulk", polyclonal lymphocyte cultures; "line",
T cell line (culture with >99% CD8+ cells, >75% positive
for the fluorescent tetramer HLA-A*0201/hTERT540-548); "clones",
monoclonal CD8+ T cells; +, done; -, not done.
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