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Figure 8

Specific cytotoxicity of the T cell clone NW1538-CTL-1/1 against NY-ESO-1 p94-102 and naturally processed NY-ESO-1. Cytotoxicity of the T cell clone NW1539-CTL-1/1 against NY-ESO-1 p94-102 peptide-pulsed T2.A3 cells, autologous vvESO-transduced NW1539-EBV B cells, NW1539-MEL-1 and LB39 melanoma cells as assessed in a standard 51chromium release assay. No reactivity was found against T2.A3, untreated NW1539-EBV-B cells and K562 cells. Effector cells were used at effector to target ratios of 60:1 (black), 30:1 (checkered), 10:1 (white) and 1:1 (striped).

 

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