Immunoscreening of cDNA expression libraries from breast cancer with autologous and allogeneic patient sera (SEREX).
Tumor Type
Serum Source
Breast Cancer cDNA Library Designation
Number of Distinct Antigens Identified by SEREX
(Known1/Novel2)
Antigens with Non-Cancer Related Serological Profiles
Antigens with Cancer-related Serological Profiles
Invasive ductal carcinoma
Autologous
184
17 (12/5)
13
4
297
6 (6/0)
5
1
257
9 (8/1)
Invasive pleomorphic lobular carcinoma
263
13 (9/4)
8
SK-BR-3 (established breast cancer cell line)
Allogeneic-1
9993
34 (27/7)
14
20
SK-BR-3
Allogeneic-2
15 (12/3)
9
6
Totals
94 (74/20)
50
44
1Identical to GenBank Entries. 2Identities limited to expressed sequence tags (ESTs).
Copyright © 2001 by Matthew J. Scanlan