|
Human
CT (Cancer/Testis) Antigens.
|
CTa
|
System
|
#
Genes
|
Chromosome
Location
|
Detection
Systemb
|
References
|
|
1
|
MAGE
|
16
|
Xq28/Xp21
|
T,
Ab
|
7,10,12,13
|
|
2
|
BAGE
|
2
|
Unknown
|
T
|
14
|
|
3
|
GAGE
|
9
|
Xp11
|
T
|
15,16
|
|
4
|
SSX
|
>5
|
Xp11
|
Ab
|
10,17
|
|
5
|
NY-ESO-1
LAGE-1
|
2
|
Xq28
|
Ab,
T, RDA
|
18,19
|
|
6
|
SCP-1
|
3
|
1p12-p13
|
Ab
|
20
|
|
7
|
CT7
/ MAGE-C1
|
1
|
Xq26
|
Ab,
RDA
|
21,22
|
|
8
|
CT8
|
1
|
Unknown
|
Ab
|
23
|
|
9
|
CT9
|
1
|
1p
|
Ab
|
24
|
|
10
|
CT10
/ MAGE-C2
|
1
|
Xq27
|
RDA,
Ab
|
25,26
|
|
11
|
CTp11
|
1
|
Xq26
-Xq27
|
-c
|
27
|
|
12
|
SAGE
|
1
|
Xq28
|
RDA
|
28
|
|
13
|
cTAGE-1
|
1
|
18p11
|
Ab
|
29
|
|
14
|
OY-TES-1
|
2
|
12p12-p13
|
Ab
|
30
|
aNumbered according to the CT nomenclature proposed
by Old & Chen (11).
bAbbreviations: Ab, antibody; T, CD8+ T
cell; RDA, representational difference analysis.
cDefined by differential mRNA expression in a parental
vs. metastatic melanoma cell variant.
|
