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Standard Abbreviations

>A-C >D-F >G-L >M-Q >R-Z

April 2008

The abbreviations listed here are used without definition in articles published in the Journal.

To search for specific terms, please use your browser's "Edit - Find" option.
Please use the Feedback form to suggest additional abbreviations.

 

A - C

aa, amino acid (only with number)
Ab, antibody
ADCC, antibody-dependent cell-mediated cytotoxicity
Ag, antigen
AML, acute myeloid leukemia
ANOVA, analysis of variance
APC, antigen-presenting cell
ATP, adenosine triphosphate
bp, base pair (only with numbers)
BrdU, 5-bromodeoxyuridine
BSA, bovine serum albumin
C, complement
C', activated complement
cAMP, cyclic AMP
CD, cluster of differentiation
CDC, complement-dependent cytotoxicity
cDNA, complementary DNA
CFA, complete Freund's adjuvant
CFSE, 5- (and 6-)carboxyfluorescein diacetate succinimidyl ester
CFU, colony-forming unit (only with numbers)
cGy, centiGray (only with numbers)
CHO, Chinese hamster ovary
Ci, Curie (only with numbers)
cm, centimeter (only with numbers)
CML, chronic myelogenous leukemia
CMV, cytomegalovirus
cpm, counts per minute (only with numbers)
CTL, cytotoxic T lymphocyte

 

D - F

d, day (only with numbers)
Da, Dalton (only with numbers)
DAPI, 4',6-diamidino-2-phenylindole
DC, dendritic cell
DEAE, diethylaminoethyl
DHFR, dihydrofolate reductase
DMEM, Dulbecco's modified Eagle's medium
DMSO, dimethylsulfoxide
DNA, deoxyribonucleic acid
DTH, delayed-type hypersensitivity
DTT, dithiothreitol
E. coli, Escherichia coli
E/T ratio, effector to target cell ratio
EBV, Epstein-Barr virus
EDTA, ethylenediaminetetraacetic acid
EGFP, enhanced green fluorescent protein
ELISA, enzyme-linked immunosorbent assay
ELISPOT, enzyme-linked immunospot
EMBL, European Molecular Biology Laboratory
EORTC, European Organisation for Research and Treatment of Cancer
ER, endoplasmic reticulum
EST, expressed sequence tag
Fab, IgG fragment with specific antigen binding
FACS®, fluorescence-activated cell sorter (registered trademark)
FBS, fetal bovine serum
Fc, IgG fragment crystallizable
FCS, fetal calf serum
FISH, fluorescence in situ hybridization
FITC, fluorescein isothiocyanate
Fv, IgG fragment variable

 

G - L

g, unit of gravity
GFP, green fluorescent protein
GM-CSF, granulocyte-macrophage colony stimulating factor
h, hour (only with numbers)
HACA, human anti-chimeric antibodies
HAHA, human anti-human antibodies
HAMA, human anti-mouse antibodies
Hepes or HEPES, N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid
HHV, human herpes virus
HIV, human immunodeficiency virus
HLA, human leukocyte antigen
HPLC, high performance or high pressure liquid chromatography
HPV, human papilloma virus
HRP, horseradish peroxidase
i.d., intradermal
IFA, incomplete Freund's adjuvant
IFN, interferon
Ig (IgG,IgM), immunoglobulin (gamma, mu isotype)
IL, interleukin
i.m., intramuscular
i.p., intraperitoneal
IPTG, isopropyl b-d-thiogalactoside
IU, international unit (only with numbers)
i.v., intravenous
kb, kilobase (only with numbers)
kbp, kilobase pairs (only with numbers)
kDa, kilodalton (only with numbers)
LAK, lymphokine-activated killer (cells)
LB, Luria-Bertani or Lenox broth
LC, Langerhans cell
LN, lymph node
LPS, lipopolysaccharide

 

M - Q

2-ME, 2-mercaptoethanol
M, molar (only with numbers)
mAb, monoclonal antibody
MACS, magnetic-activated cell sorting
MEM, minimum essential medium
mg, milligram (only with numbers)
MHC, major histocompatibility complex
min, minute (only with numbers)
MLR, mixed lymphocyte reaction
mM, millimolar (only with numbers)
mo, month (only with numbers)
mol, mole
MOPS, 4-morpholinepropanesulfonic acid
Mr, relative molecular mass
MRI, magnetic resonance imaging
mRNA, messenger RNA
MTT, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
NCBI, National Center for Biotechnology Information
NCI, National Cancer Institute
NIH, National Institutes of Health
Ni-NTA, nickel-nitrilotriacetic acid
NK, natural killer (cells)
NKT, natural killer T (cells)
NOD, nonobese diabetic
NSCLC, non-small cell lung cancer
nt, nucleotide (only with numbers)
OD, optical density
OVA, ovalbumin
P, probability
PBL, peripheral blood lymphocyte
PBMC, peripheral blood mononuclear cell
PBS, phosphate-buffered saline
PCR, polymerase chain reaction
PCR-RFLP, PCR-restriction fragment length polymorphism
PE, phycoerythrin
PFU or pfu, plaque-forming unit
PHA, phytohemagglutinin
pI, isoelectric point
PI, propidium iodide
PMSF, phenylmethylsulfonyl fluoride

 

R - Z

RACE, rapid amplification of cDNA ends
rDNA, ribosomal DNA
RIA, radioimmunoassay
RNA, ribonucleic acid
RPMI, Roswell Park Memorial Institute
rRNA, ribosomal RNA
RT-PCR, reverse transcriptase polymerase chain reaction
s, second (only with numbers)
SAGE, serial analysis of gene expression
s.c., subcutaneous
scFv, single-chain variable fragment
SCID, severe combined immunodeficiency
SD, standard deviation
SDS, sodium dodecyl sulfate
SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis
SE, standard error
SEM, standard error of the mean
siRNA, small interfering RNA
SSC, standard saline citrate
SV40, simian virus 40
TBS, Tris-buffered saline
TCR, T cell receptor
TdR, thymidine deoxyribose
TFA, trifluoroacetic acid
TGF, transforming growth factor
Th1,Th2 T helper cell
TIL, tumor-infiltrating lymphocyte
TNF, tumor necrosis factor
Treg, regulatory T (cells)
Tris, tris(hydroxymethyl)aminomethane
U, unit (only with numbers)
UV, ultraviolet
vol, volume
VSV, vesicular stomatitis virus
wk, week (only with numbers)
yr, year (only with numbers)

 

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