The original text of this review was published as:

Chen YT, Scanlan MJ, Obata Y, Old LJ. Identification of human tumor antigens by serological expression cloning. In: Rosenberg SA, editor. Principles and practice of the biologic therapy of cancer. 3rd ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2000. pp. 557-70. ISBN 0-7817-2272-1

Permission has been granted to Cancer Immunity to reproduce the text and have it updated by one of the original authors in order to provide a "living" review online. This review should be cited as follows:

Chen YT. Identification of human tumor antigens by serological expression cloning: an online review on SEREX. Cancer Immun 2004 [updated 2004 Mar 10; cited 2004 Apr 1]. URL: http://www.cancerimmunity.org/SEREX/

The text is divided into the following sections:

• Introduction
• Methodology
  • SEREX: The Technique and Steps Involved in the Analysis of SEREX-defined Antigens
  • Modifications in the SEREX Technique
• SEREX-defined Antigens by Tumor Type
  • Melanoma
  • Esophageal Cancer
  • Colon Cancer
  • Gastric Cancer
  • Renal Cancer
  • Lung Cancer
  • Breast Cancer
  • Prostate Cancer
  • Hepatic Cancer
  • Ovarian Cancer
  • Sarcoma
  • Neuroblastoma
  • Other Solid Tumors
  • Hodgkin's and Non-Hodgkin's Lymphoma
  • Leukemia
• Classification of SEREX-defined Antigens
  • Cancer-Testis Antigens
  • Mutational Antigens
  • Differentiation Antigens
  • Viral Antigens
• Immunogenicity of SEREX-defined Antigens
  • Basis for the Immunogenicity of SEREX-defined Antigens
  • Seroepidemiology of SEREX-defined Antigens
  • T-cell Recognition of SEREX-defined Antigens
  • Cancer Immunome
• References

Contact

Address correspondence to:

Yao-Tseng Chen
Dept. of Pathology
Weill Medical College of Cornell University
New York, NY 10021
USA